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Hemi-Sync is short for Hemispheric Synchronization, also known as brainwave synchronization. Monroe indicated that the technique synchronizes the two hemispheres of one’s brain, thereby creating a ‘frequency-following response’ designed to evoke certain effects. Hemi-Sync has been used for many purposes, including relaxation and sleep induction, learning and memory aids, helping those with physical and mental difficulties, and reaching altered states of consciousness through the use of sound.

The technique involves using sound waves to entrain brain waves. Wearing headphones, Monroe claimed that brains respond by producing a third sound (called binaural beats) that encouraged various brainwave activity changes.[4][5] In 2002, a University of Virginia presentation at the Society for Psychophysiologial Research demonstrated that EEG changes did not occur when the standard electromagnetic headphones of Monroe’s setup were replaced by air conduction headphones connected to a remote transducer by rubber tubes, suggesting that the basis for the entrainment effects is electromagnetic rather than acoustical in nature.

Replicated, double-blind, randomized trials on anesthetized patients have found Hemi-Sync effective as a partial replacement for fentanyl during surgery.[6][7] A similar study found it ineffective at replacing propofolhowever.[8]




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